Partially Local Multi-Way Alignments

نویسندگان

  • Nancy Retzlaff
  • Peter F. Stadler
چکیده

With increasing computational resources exact solutions to 3and 4-way alignments have become feasible in practise. In the pairwise case there is a clear distinction between local and global alignments. As more sequences considered this distinction, which can in fact be made independently for both ends of each sequence, gives rise to a rich set of partially local alignments. So far these have remained largely unexplored. Here we propose a very general framework for this class of problems and show how exact dynamic programming solutions can be constructed in principled manner. 1998 ACM Subject Classification I.2.8: Dynamic programming, F.2.2: Computations on discrete structures

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تاریخ انتشار 2017